Results for 'Gerard Peter Brennan'

977 found
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  1. Reimagining the new pedagogical possibilities for universities post-Covid-19.Michael A. Peters, Fazal Rizvi, Gary McCulloch, Paul Gibbs, Radhika Gorur, Moon Hong, Yoonjung Hwang, Lew Zipin, Marie Brennan, Susan Robertson, John Quay, Justin Malbon, Danilo Taglietti, Ronald Barnett, Wang Chengbing, Peter McLaren, Rima Apple, Marianna Papastephanou, Nick Burbules, Liz Jackson, Pankaj Jalote, Mary Kalantzis, Bill Cope, Aslam Fataar, James Conroy, Greg Misiaszek, Gert Biesta, Petar Jandrić, Suzanne S. Choo, Michael Apple, Lynda Stone, Rob Tierney, Marek Tesar, Tina Besley & Lauren Misiaszek - forthcoming - Educational Philosophy and Theory:1-44.
    Michael A. Petersa and Fazal Rizvib aBeijing Normal University, Beijing, PR China; bMelbourne University, Melbourne, Australia Our minds are still racing back and forth, longing for a return to ‘no...
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  2.  43
    A handbook of logic.Joseph Gerard Brennan - 1957 - New York,: Harper.
    This handbook introduces the reader both to the tradi tional logic of the syllogism and to modern symbolic logic.
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  3.  53
    Markets Without Limits: Moral Virtues and Commercial Interests.Jason Brennan & Peter Jaworski - 2015 - London: Routledge.
    May you sell your vote? May you sell your kidney? May gay men pay surrogates to bear them children? May spouses pay each other to watch the kids, do the dishes, or have sex? Should we allow the rich to genetically engineer gifted, beautiful children? Should we allow betting markets on terrorist attacks and natural disasters? Most people shudder at the thought. To put some goods and services for sale offends human dignity. If everything is commodified , then nothing is (...)
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  4. Markets without Symbolic Limits.Jason Brennan & Peter Martin Jaworski - 2015 - Ethics 125 (4):1053-1077.
    Semiotic objections to commodification hold that buying and selling certain goods and services is wrong because of what market exchange communicates or because it violates the meaning of certain goods, services, and relationships. We argue that such objections fail. The meaning of markets and of money is a contingent, socially constructed fact. Cultures often impute meaning to markets in harmful, socially destructive, or costly ways. Rather than semiotic objections giving us reason to judge certain markets as immoral, the usefulness of (...)
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  5.  6
    Whitehead on Metaphysics.Joseph Gerard Brennan - 1972 - Philosophy Today 16 (3):210-219.
  6.  36
    Whitehead on Plato's cosmology.Joseph Gerard Brennan - 1971 - Journal of the History of Philosophy 9 (1):67-78.
  7.  5
    Ethics and morals.Joseph Gerard Brennan - 1973 - New York,: Harper & Row.
  8.  8
    Liberty, equality and poverty [This article is the text of the Ozanam Lecture (1999: Melbourne).].Gerard Brennan - 2000 - The Australasian Catholic Record 77 (2):175.
  9. The meaning of philosophy.Joseph Gerard Brennan - 1953 - New York,: Harper & Row.
     
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  10. The meaning of philosophy.Joseph Gerard Brennan - 1953 - New York,: Harper.
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  11.  25
    The Life and Mind of John Dewey.Joseph Gerard Brennan & Patricia Albjerg Graham - 1974 - Educational Studies: A Jrnl of the American Educ. Studies Assoc 5 (1&2):27-31.
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  12.  31
    Thomas mann and the business ethic.Joseph Gerard Brennan - 1985 - Journal of Business Ethics 4 (5):401-407.
    Son of a North German businessman, Thomas Mann chose as theme for his early narrative work the conflict between the standards and values of business and those of the artist-writer.Buddenbrooks andTonio Kröger exhibit the tension of values in opposite ways. InThe Magic Mountain, Mann expands his canvas to include military as well as business values in their relation to the creative potential in a young engineer who exiles himself to an Alpine tuberculosis sanatorium to enjoy a unique educational experience. Mann (...)
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  13.  8
    Perspectives on the Emergence of Scientific Disciplines.Gerard Lemaine, Roy Macleod, Michael Mulkay & Peter Weingart (eds.) - 1976 - De Gruyter.
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  14.  17
    Balancing Change and Tradition in Global Education Reform.Gérard Bonnet, Mary Canning, Kai-Ming Cheng, Terry J. Crooks, Luis Crouch, Ori Eyal, Eva Forsberg, Phyllis Ghim-Lian Chew, Ratna Ghosh, Martin Gustafsson, Batia P. Horsky, Dan Inbar, Barbara M. Kehm, Stephen T. Kerr, Allan Luke, Ulf P. Lundgren, Robert W. McMeekin, Adam Nir, Peter Schrag, Hasan Simsek, Ryo Watanabe, Alison Wolf & Ali Yildirim (eds.) - 2010 - R&L Education.
    Balancing Change and Tradition in Global Education Reform is an invaluable resource for policymakers, faculty, students, and anyone interested in how decisions made about the education system ultimately affect the quality of education, educational access, and social justice.
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  15.  81
    In Defense of Commodification.Jason Brennan & Peter Jaworski - 2015 - Moral Philosophy and Politics 2 (2):357-377.
    We aim to show anti-commodification theorists that their complaints about the scope of the market are exaggerated. There are we agree things that should not be bought and sold but that’s only because they are things people shouldn’t have or do or exchange in the first place. Beyond that we argue there are legitimate moral worries about how we buy trade and sell but no legitimate worries about what we buy trade and sell. In almost every interesting case where they (...)
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  16.  53
    If You Can Reply for Money, You Can Reply for Free.Jason Brennan & Peter M. Jaworski - 2017 - Journal of Value Inquiry 51 (4):655-661.
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  17.  65
    Paper: Should the practice of medicine be a deontological or utilitarian enterprise?Gerard Garbutt & Peter Davies - 2011 - Journal of Medical Ethics 37 (5):267-270.
    There is currently an unrecognised conflict between the utilitarian nature of the overall NHS and the basic deontology of the doctor-patient interaction. This conflict leads to mistrust and misunderstanding between managers and clinicians. This misunderstanding is bad for both doctors and managers, and also leads to waste of time and resources, and poorer services to patients. The utilitarian thinkers tend to value finite, short term, evidence based technical interventions, delivered according to specifications and contracts. They appear happy to break care (...)
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  18. An epistemological approach to modeling: Cases studies and implications for science teaching.Gérard Sensevy, Andrée Tiberghien, Jérôme Santini, Sylvain Laubé & Peter Griggs - 2008 - Science Education 92 (3):424-446.
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  19.  32
    I’ll Pay You Ten Bucks Not to Murder Me.Jason Brennan & Peter Jaworski - 2016 - Business Ethics Journal Review 4 (9):53-58.
    James Stacey Taylor offers three interpretations of our thesis, and argues that only one of them goes through. His point is to clarify our view rather than critique our position. In this brief response, we argue that, upon further clarification, we could endorse at least one of the other interpretations, though as Taylor notes, we don’t need to for our book’s thesis to go through.
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  20.  17
    I’ll Pay You Ten Bucks Not to Murder Me.Jason Brennan & Peter Jaworski - 2016 - Business Ethics Journal Review 4 (9):53-58.
    James Stacey Taylor offers three interpretations of our thesis, and argues that only one of them goes through. His point is to clarify our view rather than critique our position. In this brief response, we argue that, upon further clarification, we could endorse at least one of the other interpretations, though as Taylor notes, we don’t need to for our book’s thesis to go through.
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  21.  56
    Come On, Come On, Love Me for the Money.Jason Brennan & Peter M. Jaworski - 2018 - Business Ethics Journal Review 6 (6):30-35.
    Jacob Sparks critiques our recent work on commodification by arguing that purchasing love indicates one has defective preferences. We argue A) it is possible to purchase these things without having defective preferences, B) Sparks has not shown that acting such defective preferences is morally wrong, C) that Sparks’ misunderstands the Brennan–Jaworski Thesis, and so has not produced a counterexample to it, and finally D) that when we examine the processes by which love is gifted, it is unclear whether these (...)
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  22.  60
    Emotion work and emotional exhaustion in teachers: The job and individual perspective.Gérard Näring, Peter Vlerick & Bart Van de Ven - 2012 - Educational Studies 38 (1):63-72.
    Teaching requires much emotion work which takes its toll on teachers. Emotion work is usually studied from one of two perspectives, a job or an individual perspective. In this study, we assessed the relative importance of these two perspectives in predicting emotional exhaustion. More than 200 teachers completed a questionnaire comprising the DISQ , the Dutch Questionnaire on Emotional Labour , and the UBOS . In line with previous studies, our findings indicated that emotional exhaustion is positively associated with emotional (...)
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  23.  38
    How clocks define physical time.Peter W. Evans, Gerard J. Milburn & Sally Shrapnel - unknown
    It is the prevailing paradigm in contemporary physics to model the dynamical evolution of physical systems in terms of a real parameter conventionally denoted as 't' ('little tee'). We typically call such dynamical models laws of nature' and t we call 'physical time'. It is common in the philosophy of time to regard t as time itself, and to take the global structure of general relativity as the ultimate guide to physical time, and so consequently the true nature of time. (...)
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  24. New problems in medical ethics.Peter Flood & Malachy Gerard Carroll (eds.) - 1953 - Westminster, Md.,: Newman Press.
     
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  25.  9
    Genetic discrimination: transatlantic perspectives on the case for a European-level legal response.Gerard Quinn, Aisling De Paor & Peter David Blanck (eds.) - 2015 - New York, NY: Routledge.
    The science and technology of genetic testing is rapidly advancing with the consequences that genetic testing may well offer the prospect of being able to detect the onset of future disabilities. Some recent research also indicates that certain behavioural profiles may have a strong genetic basis, such as the determination to succeed and win or the propensity for risk-taking, which may be of interest to third parties. However, as this technology becomes more prevalent there is a danger that the genetic (...)
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  26.  6
    An appeal of the Moriscos to the Mamluk sultan and its counterpart to the Ottoman court: Textual analysis, context, and wider historical background.Gerard A. Wiegers & Peter Sjoerd van Koningsveld - 1999 - Al-Qantara 20 (1):161-190.
    Este artículo tiene por objeto dar una versión diferente y más breve del poema que contiene una demanda morisca de ayuda al Imperio Otomano, poema estudiado por James Monroe en Al-Andalus XXXI, 281-303. Esta versión indica que había habido otra demanda similar por parte de los moriscos al sultán mameluco de El Cairo, y que ésta era la original. El artículo contiene: 1) un análisis comparativo de las versiones de la casida dirigidas a los mamelucos y a los otomanos, 2) (...)
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  27.  15
    The islamic statute of the Mudejars in the light of a new source.Gerard A. Wiegers & Peter Sjoerd van Koningsveld - 1996 - Al-Qantara 17 (1):19-58.
    El trabajo expone, analiza, y evalúa los datos de una nueva fuente sobre las visiones jurídicas de los ‛ulamā’ con respecto al estatuto islámico de las comunidades islámicas bajo dominio cristiano en la Península Ibérica desde el siglo XII hasta el siglo XVI. Se trata de una fetua desconocida e inédita del sabio andalusí Ibn Rabī‛ y fetuas desconocidas de los principales cadíes de los cuatro madhabs sunníes en El Cairo hacia 1510 A.D. Muy probablemente, hay que relacionar la primera (...)
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  28.  26
    The Parchment of the "Torre Turpiana": the original document and its early interpreters.Gerard A. Wiegers & Peter Sjoerd van Koningsveld - 2003 - Al-Qantara 24 (2):327-358.
    Este artículo está dedicado al famoso pergamino encontrado en 1588 en el antiguo minarete de la que había sido mezquita aljama de Granada, con textos en árabe, latín y castellano. Junto con los libros plúmbeos descubiertos en diversas cuevas a las afueras de la ciudad entre 1595 y 1600, el pergamino está en los orígenes de un importante culto nacional. El artículo presenta un análisis de la composición y escritura del pergamino y pasa revista a las trascripciones y traducciones que (...)
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  29. Le Paysage d'orage avec Pyrame et Thisbé, de Nicolas Poussin: Nouvelles découvertes dur le genèse du Paysage d'Orage avec Pyrame et Thisbé de Nicolas Poussin-Etat de conservation et restauration.Michael Maek-Gérard & Peter Waldeis - 1994 - Techne 1:53-64.
  30. Making productive use of students' initial conceptions in developing the concept of force.Peter J. J. M. Dekkers & Gerard D. Thijs - 1998 - Science Education 82 (1):31-51.
     
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  31.  23
    Markets without Symbolic Limits.Jason Brennan and Peter Martin Jaworski - 2015 - Ethics 125 (4):1053-1077,.
  32.  21
    Magnus Hirschfeld, his biographies and the possibilities and boundaries of 'biography' as 'doing history'.Toni Brennan & Peter Hegarty - 2009 - History of the Human Sciences 22 (5):24-46.
    This article considers the two major biographies of sexologist Magnus Hirschfeld, MD (1868—1935), an early campaigner for ‘gay rights’ avant la lettre. Like him, his first biographer Charlotte Wolff (1897—1986) was a Jewish doctor who lived and worked in Weimar Republic Berlin and fled Germany when the Nazi regime came to power. When researching Hirschfeld’s biography (published in English in 1986) Wolff met a librarian and gay activist, Manfred Herzer, who would eventually be a cofounder of the Gay Museum in (...)
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  33.  4
    War and Social Theory: Reflections after Kosovo: Introduction.Peter Wagner, Heidrun Friese & Gerard Delanty - 2001 - European Journal of Social Theory 4 (1):5-10.
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  34.  27
    Making sense of place: multidisciplinary perspectives.Ian Convery, Gerard Corsane & Peter Davis (eds.) - 2012 - Rochester, NY: Boydell Press.
    Essays dealing with the question of how "sense of place" is constructed, in a variety of locations and media.
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  35.  3
    Ideal und Wirklichkeit der bildenden Kunst im späten 18. Jahrhundert.Herbert Beck, Peter Bol & Eva Maek-Gérard - 1984
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  36.  14
    Development and Initial Validation of the Italian Mood Scale (ITAMS) for Use in Sport and Exercise Contexts.Alessandro Quartiroli, Peter C. Terry & Gerard J. Fogarty - 2017 - Frontiers in Psychology 8.
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  37.  70
    Reimagining the new pedagogical possibilities for universities post-Covid-19: An EPAT Collective Project.Lauren Misiaszek, Tina Besley, Marek Tesar, Rob Tierney, Lynda Stone, Michael Apple, Suzanne S. Choo, Petar Jandrić, Gert Biesta, Greg Misiaszek, James Conroy, Aslam Fataar, Bill Cope, Mary Kalantzis, Pankaj Jalote, Liz Jackson, Nick Burbules, Marianna Papastephanou, Rima Apple, Peter McLaren, Wang Chengbing, Ronald Barnett, Danilo Taglietti, Justin Malbon, John Quay, Susan Robertson, Marie Brennan, Lew Zipin, Yoonjung Hwang, Moon Hong, Radhika Gorur, Paul Gibbs, Gary McCulloch, Fazal Rizvi & Michael A. Peters - 2022 - Educational Philosophy and Theory 54 (6):717-760.
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  38.  8
    Conceptual Structures: Knowledge Representations as Interlingua: 4th International Conference on Conceptual Structures, Iccs'96, Sydney, Australia, August 19 - 22, 1996, Proceedings.Peter W. Eklund, Gerard Ellis & Graham Mann - 1996 - Springer Verlag.
    This volume constitutes the refereed proceedings of the Fourth International Conference on Conceptual Structures, ICCS '96, held in Sydney, Australia, in August 1996. The book presents five full papers by the invited speakers together with 15 revised full papers selected for presentation at the conference from a respectable number of submissions. The issues addressed are natural language processing, information retrieval, graph operations, conceptual graph and Peirce theory, knowledge acquisition, theorem proving and CG programming, and order-based organisation and encoding.
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  39. Bonner, Anthony. The Art and Logic of Ramon Llull: A User's Guide. Studien und Texte zur Geistesge-schichte des Mittelalters, 95. Leiden-Boston: Brill, 2007. Pp. xx+ 333. Cloth, $150.00. Boros, Gábor, Herman De Dijn, and Martin Moors, editors. The Concept of Love in 17th and 18th Century Philosophy. Leuven: Leuven University Press, 2007. Pp. 269. Paper,€ 35.50. Boulnois, Olivier. Au-delà de l'image, Une archéologie du visual au Moyen Âge, Ve-XVIe siècle. Paris: Des. [REVIEW]Roger T. Ames, Peter D. Hershock, Andrew R. Bailey, Samantha Brennan, Will Kymlicka, Jacob Levy, Alex Sager & Clark Wolf - 2008 - Journal of the History of Philosophy 46 (4):653-56.
  40.  12
    Stepping down from mere appearance: Modelling the 'actuality' of time.Sally Shrapnel, Peter W. Evans & Gerard J. Milburn - unknown
    In her paper, 'The Open Universe: Totality, Self-reference and Time', Ismael argues that the agent experience of dynamic time, in which the world comes into being, is more than 'mere appearance'. The key to her argument is that the actual world includes agents (minds) and their corresponding agential (mental) activity, which Ismael describes as 'the crucial step down from 'mere appearance' to actuality'. We present here a model of an agent as a complex physical system with a view to providing (...)
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  41. The polemical works of Muhammad al-Qaysi (fl.1309) and their circulation in Arabic and Aljamiado among the Mudejars in the fourteenth century.Peter Sjoerd van Koningsveld & Gerard A. Wiegers - 1994 - Al-Qantara 15 (1):163-200.
  42.  12
    Impact of the National Practitioner Data Bank on Resolution of Malpractice Claims.Teresa M. Waters, David M. Studdert, Troyen A. Brennan, Eric J. Thomas, Orit Almagor, Martha Mancewicz & Peter P. Budetti - 2003 - Inquiry: The Journal of Health Care Organization, Provision, and Financing 40 (3):283-294.
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  43.  27
    Bookreviews.P. C. Beentjes, B. J. Koet, Eric Ottenheijm, P. van Geest, Bart J. Koet, Gerard Rouwhorst, Ton Meijers, Marc Lindeijer, Walter Van Herck, H. J. Adriaanse, Guido Vanheeswijck, Péter Losonczi, Edwin Koster & Frank G. Bosman - 2009 - Bijdragen 70 (3):361-379.
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  44.  37
    Catholicism Engaging Other Faiths: Vatican Ii and its Impact.Michael Amaladoss S. J., Roberto Catalano, Francis X. Clooney S. J., Archbishop Michael L. Fitzgerald, Richard Girardin, Roger Haight S. J., Sallie B. King, Vladimir Latinovic, Leo D. Lefebure, Archbishop Felix Machado, Gerard Mannion, Alexander E. Massad, Sandra Mazzolini, Dawn M. Nothwehr O. S. F., John T. Pawlikowski O. S. M., Peter C. Phan, Jonathan Ray, William Skudlarek O. S. B., Cardinal Jean-Louis Tauran, Jason Welle O. F. M. & Taraneh R. Wilkinson (eds.) - 2018 - Springer Verlag.
    This book assesses how Vatican II opened up the Catholic Church to encounter, dialogue, and engagement with other world religions. Opening with a contribution from the President of the Pontifical Council for Interreligious Dialogue, Cardinal Jean-Louis Tauran, it next explores the impact, relevance, and promise of the Declaration Nostra Aetate before turning to consider how Vatican II in general has influenced interfaith dialogue and the intellectual and comparative study of world religions in the postconciliar decades, as well as the contribution (...)
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  45.  17
    Shakespeare's Last Plays: Essays in Literature and Politics.John E. Alvis, Glenn C. Arbery, David N. Beauregard, Paul A. Cantor, John Freeh, Richard Harp, Peter Augustine Lawler, Mary P. Nichols, Nathan Schlueter, Gerard B. Wegemer & R. V. Young - 2002 - Lexington Books.
    What were Shakespeare's final thoughts on history, tragedy, and comedy? Shakespeare's Last Plays focuses much needed scholarly attention on Shakespeare's "Late Romances." The work--a collection of newly commissioned essays by leading scholars of classical political philosophy and literature--offers careful textual analysis of Pericles, Prince of Tyre, Cymbeline, The Winter's Tale, The Tempest, All is True, and The Two Noble Kinsmen. The essays reveal how Shakespeare's thought in these final works compliments, challenges, fulfills, or transforms previously held conceptions of the playwright (...)
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  46.  19
    Cross-Cultural Validation of Mood Profile Clusters in a Sport and Exercise Context.Alessandro Quartiroli, Renée L. Parsons-Smith, Gerard J. Fogarty, Garry Kuan & Peter C. Terry - 2018 - Frontiers in Psychology 9:408351.
    Mood profiling has a long history in the field of sport and exercise. Several novel mood profile clusters were identified and described in the literature recently (Parsons-Smith, Terry, & Machin, 2017). In the present study, we investigated whether the same clusters were evident in an Italian language, sport and exercise context. The Italian Mood Scale (ITAMS; Quartiroli, Terry, & Fogarty, 2017) was administered to 950 Italian-speaking sport participants (659 females, 284 males, 7 unspecified; age range = 16–63 yr., M = (...)
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  47.  11
    Bioethics: A Culture War.: Nicholas C. Lund-Molfese, Michael Kelly, Francis Cardinal George, Jean Bethke Elshtain, Patrick Lee, Peter Kreeft, Charles E. Rice & Gerard V. Bradley (eds.) - 2004 - Upa.
    The purpose of this valuable book is to consider recent cultural trends in bioethics from a Catholic perspective. Bioethics is intended for a lay audience interested in understanding bioethical issues from a Catholic perspective.
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  48.  41
    Poems of Gerard Manley HopkinsGerard Manley Hopkins ; A Study of Poetic Idiosyncrasy in Relation to Poetic TraditionGerard Manley Hopkins; A Critical Essay towards the Understanding of His PoetryImmortal Diamond: Studies in Gerard Manley Hopkins.Craig la Driere, W. H. Gardner, Gerard Manley Hopkins, W. A. M. Peters & Norman Weyand - 1950 - Journal of Aesthetics and Art Criticism 9 (2):153.
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  49.  40
    The IARC Monographs: Updated procedures for modern and transparent evidence synthesis in cancer hazard identification.Jonathan M. Samet, Weihsueh A. Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M. Lunn, Frederick A. Beland, Lisa Bero, Patience Browne, Lin Fritschi, Jun Kanno, Dirk W. Lachenmeier, Qing Lan, Gérard Lasfargues, Frank Le Curieux, Susan Peters, Pamela Shubat, Hideko Sone, Mary C. White, Jon Williamson, Marianna Yakubovskaya, Jack Siemiatycki, Paul A. White, Kathryn Z. Guyton, Mary K. Schubauer-Berigan, Amy L. Hall, Yann Grosse, Véronique Bouvard, Lamia Benbrahim-Tallaa, Fatiha El Ghissassi, Béatrice Lauby-Secretan, Bruce Armstrong, Rodolfo Saracci, Jiri Zavadil, Kurt Straif & Christopher P. Wild - unknown
    The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...)
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  50. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.David C. Whitcomb, Jessica LaRusch, Alyssa M. Krasinskas, Lambertus Klei, Jill P. Smith, Randall E. Brand, John P. Neoptolemos, Markus M. Lerch, Matt Tector, Bimaljit S. Sandhu, Nalini M. Guda, Lidiya Orlichenko, Samer Alkaade, Stephen T. Amann, Michelle A. Anderson, John Baillie, Peter A. Banks, Darwin Conwell, Gregory A. Coté, Peter B. Cotton, James DiSario, Lindsay A. Farrer, Chris E. Forsmark, Marianne Johnstone, Timothy B. Gardner, Andres Gelrud, William Greenhalf, Jonathan L. Haines, Douglas J. Hartman, Robert A. Hawes, Christopher Lawrence, Michele Lewis, Julia Mayerle, Richard Mayeux, Nadine M. Melhem, Mary E. Money, Thiruvengadam Muniraj, Georgios I. Papachristou, Margaret A. Pericak-Vance, Joseph Romagnuolo, Gerard D. Schellenberg, Stuart Sherman, Peter Simon, Vijay P. Singh, Adam Slivka, Donna Stolz, Robert Sutton, Frank Ulrich Weiss, C. Mel Wilcox, Narcis Octavian Zarnescu, Stephen R. Wisniewski, Michael R. O'Connell, Michelle L. Kienholz, Kathryn Roeder & M. Micha Barmada - unknown
    Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...)
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